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Hyperplasia Background


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WARNING: What follows is extremely intense and not for beginners. In fact, I’d tell you that you need a minimum of 10 years under the iron before attempting it. Extreme care should be taken not to over-do it, as a severe medical condition called rhabdomyolosis is possible. Rhabdo is the excessive breakdown of muscle tissue, and warning signs include extreme thirst, dark urine and extremely sore muscles.  Always get clearance from a qualified medical practitioner prior to beginning something like this. You are encouraged to get blood work before, during and after given the potential for too much muscle breakdown.

If you were to ask me why The Blueprint has such high success rates, I’d have to cite the training recommendations. For many, it was the first time trainees boosted both their Alpha (or 1 rep max) along with their Beta strength (total tonnage lifted, per unit of time). The other no brainer was that when you pour yourself into basic exercises, you can’t lose. You literally can’t go wrong, so long as you get the training frequency right.

Given that, I tried to answer this question: Was there another type of training stimulus, that’ll generate even more muscle growth than what I’ve already given you?

The answer isn’t “Yeah”. It’s HELL YEAH!!!

Lemme tell you why…

First, the objective here is to grow drug like amounts of muscle in record time – not set powerlifting records. That helps narrow the focus to hypertrophy, of which there are three types:


  • Myofibrillar (actual thickening of the muscle fiber)
  • Sarcoplasmic (muscle cell holds more fluid), and
  • Hyperplasia (existing muscle cells divide, then become new cells)


So the theory goes that you’re only born with so many muscle fibers. Your job is to grow them as big as possible. There’s a lot of debate as to whether or not #3 even exists, because it hasn’t been demonstrated in humans (yet). For my money though, it does. We’ll get into that in a bit, but I hate the anatomy lesson thing. The scientific names alone drive me nuts, so I’ve provided a graphic image of each below.

Here’s what they look like, under a microscope…